Scientists identify molecular system that could help develop potential...
Scientists from the University of Southampton have identified the molecular system that contributes to the harmful inflammatory reaction in the brain during neurodegenerative diseases.
View ArticleGreen tea extract interferes with the formation of amyloid plaques in...
Researchers at the University of Michigan have found a new potential benefit of a molecule in green tea: preventing the misfolding of specific proteins in the brain.
View ArticleNormal prion protein regulates iron metabolism
An iron imbalance caused by prion proteins collecting in the brain is a likely cause of cell death in Creutzfeldt-Jakob disease (CJD), researchers at Case Western Reserve University School of Medicine...
View ArticleScientists identify molecular trigger for Alzheimer's disease
Researchers have pinpointed a catalytic trigger for the onset of Alzheimer's disease – when the fundamental structure of a protein molecule changes to cause a chain reaction that leads to the death of...
View ArticleFrom trauma to tau: Researchers tie brain injury to toxic form of protein
University of Texas Medical Branch at Galveston researchers have uncovered what may be a key molecular mechanism behind the lasting damage done by traumatic brain injury.
View ArticleInterferon-beta aids balance and movement in mice with spinocerebellar ataxia 7
The group of genetic conditions known as spinocerebellar ataxias currently have no treatment or cure and are always fatal, in the case of affected children at an early age. Symptoms include a...
View ArticleRat hippocampal neurons: An executor of neuroinflammation
Recent findings suggest that Toll-like receptor 4 expressed in the central nervous system, especially in glial cells, plays a vital role in neuroinflammation and neurodegenerative conditions....
View ArticleCranial irradiation causes brain degeneration
(Medical Xpress)—Cranial irradiation saves the lives of brain cancer patients. It slows cancer progression and increases survival rates. Unfortunately, patients who undergo cranial irradiation often...
View ArticleReceptor may aid spread of Alzheimer's and Parkinson's in brain
(Medical Xpress)—Scientists at Washington University School of Medicine in St. Louis have found a way that corrupted, disease-causing proteins spread in the brain, potentially contributing to...
View ArticleLearning how the brain takes out its trash may help decode neurological diseases
Imagine that garbage haulers don't exist. Slowly, the trash accumulates in our offices, our homes, it clogs the streets and damages our cars, causes illness and renders normal life impossible.
View ArticleMore diseases responsible for dementia than previously thought, research finds
A recent study by the Clinical Institute of Neurology at the MedUni Vienna has shown that neurodegenerative diseases other than Alzheimer's disease are more common among older people than previously...
View ArticleNewly identified antibodies effectively treat Alzheimer's-like disease in mice
Alzheimer's disease is characterized by the accumulation of particular toxic proteins in the brain that are believed to underlie the cognitive decline in patients. A new study conducted in mice...
View ArticleDrug reduces brain changes, motor deficits associated with Huntington's disease
A drug that acts like a growth-promoting protein in the brain reduces degeneration and motor deficits associated with Huntington's disease in two mouse models of the disorder, according to a study...
View ArticleScientists discover trigger for protective immune response to spinal cord...
Hot on the heels of discovering a protective form of immune response to spinal cord injury, researchers at the University of Virginia School of Medicine have pinpointed the biological trigger for that...
View ArticleAstrocytes in the neurodegerating brain
Researchers from Trinity College Dublin have discovered that specialised 'astrocytes' abandon their posts as protectors and repairers of the brain when primed by the neurodegeneration of cells around...
View ArticleBlood-based biomarkers may lead to earlier diagnosis of Parkinson's disease
Parkinson's disease (PD) is a progressive neurological condition. At present, it is usually diagnosed only when motor features are present. Hence, there is a need to develop objective and measurable...
View ArticleParkinson's disease: Parkin protects from neuronal cell death
Researchers from Ludwig-Maximilians-Universitaet (LMU) in Munich identify a novel signal transduction pathway, which activates the parkin gene and prevents stress-induced neuronal cell death.
View ArticleCan your brain control how it loses control?
A new study may have unlocked understanding of a mysterious part of the brain—with implications for neurodegenerative conditions such as Alzheimer's. The results, published in Translational Vision...
View ArticleZebrafish study offers insights into nerve cell repair mechanisms
Tropical fish may hold clues that could aid research into motor neuron disease and paralysis caused by spinal cord injury.
View ArticleTracing a path toward neuronal cell death
A fruit fly model of a rare, neurodegenerative disease is helping researchers trace the series of steps that lead to neuronal cell death. Damage to astrocytes - star-shaped cells found in the brain and...
View ArticleCould a new class of fungicides play a role in autism, neurodegenerative...
Scientists at the UNC School of Medicine have found a class of commonly used fungicides that produce gene expression changes similar to those in people with autism and neurodegenerative conditions,...
View ArticleHow prions kill neurons: New culture system shows early toxicity to dendritic...
Prion diseases are fatal and incurable neurodegenerative conditions of humans and animals. Yet, how prions kill nerve cells (or neurons) remains unclear. A study published on May 26, 2016 in PLOS...
View ArticleNew ALS discovery: Scientists reverse protein clumping involved in...
In the quest to understand the driving forces behind neurodegenerative diseases, researchers in recent years have zeroed in on clumps of malfunctioning proteins thought to kill neurons in the brain and...
View ArticleCell protein offers new hope in fighting the effects of aging
A protein found within the powerhouse of a cell could be the key to holding back the march of time, research by scientists at The University of Nottingham has shown.
View ArticleHow protein fragments associated with Alzheimer's could trigger Parkinson's
Alzheimer's and Parkinson's diseases are different neurodegenerative conditions that can sometimes affect the same person, which has led scientists to investigate possible links between the two. Now...
View ArticleProtein build-up may trigger inflammation associated with Alzheimer's and...
A recent review article published online in The FASEB Journal points to the "trigger" for the inflammatory response, caused by the immune system, that precedes Alzheimer's disease and other...
View ArticleOne step closer to finding out how wine may protect your neurons
Let it be no misunderstanding: heavy alcohol intake has severe harmful effects. But already for several years, researchers have been finding that moderate wine intake can be beneficial in delaying the...
View ArticlePhagocytes in the brain—good or bad?
The role of microglial cells in neurodegenerative disease is not fully understood. But new results from researchers in Munich and Basel suggest that stimulation of this arm of the immune system might...
View ArticleSongbird study shows how estrogen may stop infection-induced brain inflammation
The chemical best-known as a female reproductive hormone—estrogen—could help fight off neurodegenerative conditions and diseases in the future. Now, new research by American University neuroscience...
View ArticleStudy reveals new mechanisms of cell death in neurodegenerative disorders
Researchers at King's College London have discovered new mechanisms of cell death, which may be involved in debilitating neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease.
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